My computer is opening applications by itself! WHAT IS WRONG?

For about a year now my computer has been going berserk....opening different applications by itself, closing applications...and while it does this, I don't have control. I have McAfee...and I did the virus scan...I have the spam remover thing....I've ran these programs, and nothing has worked. I've restored by entire computer twice, and yet still, it acts like what I've described. Is it adware? But can't that be removed by spam remover? My entire computer runs SO slow, especially online (and I have DSL), and I don't have that much stuff on my computer. I'm sure something is wrong with it...but I don't know how to find it, what it is, or how to remove it! Can you please help??

My computer is opening applications by itself! WHAT IS WRONG?live update

ima give you some apps to install and run....

http://free.grisoft.com/doc/2/

http://www.pcworld.com/downloads/file/fi...

http://www.safer-networking.org/en/downl...

its all free and easy to use have fun and gl...